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种子(Seed)是用于决定游戏地形和事件的一个随机字符串。By inputting a seed manually, one can guarantee that most randomly-generated decisions will occur the same every time. For instance, two players using the same seed will find the same items in the same locations.

Notes Regarding Seed Entry[ | ]

  • Seeds will be the same on every platform as long as the game version is also the same. For example, if you find a Rebirth seed on PC, you can use it on the 3DS version and it will be the same because the 3DS version only has Rebirth.
  • Except for some special seeds, inputting a seed will cause the 'no trophies' mark to appear. This prevents any achievements from being obtained on that particular run.
  • Special seeds do not affect level generation.
  • All alphanumeric characters are accepted except for 5, I, O, and U. On the PC version pressing the I, O, and U keys during seed entry will replace them with 1, 0, and V respectively.
  • Template:Dlc Once a special seed has been entered, it will be permanently unlocked without needing to enter the code again. Pressing Q / Left Bumper during character selection will bring up the Easter Egg Section, in which any previously unlocked game mode can be selected. Selecting multiple modes at once is also possible.
  • On the special seed selection menu, it is possible to remove a discovered seed by focusing it and pressing Q+E+Tab on keyboard or LB+RB+X on controller.

Special Seeds[ | ]

ID Seed Description Effects
Miscellaneous
16 BASE
MENT
Infinite basements The Basement repeats infinitely. Template:No unlocks
11 KEEP
AWAY
Tricky pickups Pickups mimic Isaac's movements. Template:No unlocks
72 Template:Dlc
G0NE
S00N
Pickups time out Pickups quickly fade. This includes pedestal items, shop purchases, devil deals, and the Template:S/Template:S boss chest.
33 FREE
2PAY
F2P version Isaac starts with 69 coins, but all items and consumables must be bought. Template:No unlocks
25 PAC1
F1SM
Pacifism Enemies do not take damage. All rooms are considered cleared upon entering them; doors stay open, room rewards spawn, Template:E instantly die. When in a boss room, the boss's health bar is used as a timer and slowly ticks down. At the end of the countdown, the trapdoor to the next floor appears. Template:No unlocks
32 C0ME
BACK
Enemies respawn Enemies, including bosses, respawn once Isaac leaves the room. Completing a room multiple times does not yield additional pickups. Template:No unlocks
71 Template:Dlc
N0RE
TVRN
Point of no return Boss rooms lock Isaac in, similar to the Template:E fight.
24 BRWN
SNKE
Poopy trail Isaac leaves a trail of poop behind him as he walks. Template:No unlocks
73 Template:Dlc
ALM1
GHTY
Dog mode Isaac is invincible. Template:No unlocks
55 K1DS
M0DE
Kids' co-op mode Makes co-op babies invincible. Template:No unlocks
79 Template:Dlc
GFVE
LLLL
G Fuel! Spawns a G FUEL! item in the starting room of each stage. Each copy picked up has different effects and adds various excessive "gamer style" visual and sound effects to the gameplay. Template:No unlocks
Curses
56 Template:Dlc
DARK
NESS
Permanent darkness Permanent Curse of Darkness.
57 Template:Dlc
LABY
RNTH
Inescapable labyrinth Permanent Curse of the Labyrinth. Template:No unlocks
58 Template:Dlc
L0ST
Hopelessly lost Permanent Curse of the Lost.
59 Template:Dlc
VNKN
0WN
Forever unknown Permanent Curse of the Unknown.
60 Template:Dlc
MAZE
Unending maze Permanent Curse of the Maze.
61 Template:Dlc
BL1N
D
Incurable blindness Permanent Curse of the Blind.
62 Template:Dlc
CVRS
ED
Horrible curse Permanent Curse of the Cursed.
Curse Immunity
63 Template:Dlc
N1TE
L1TE
Illuminate darkness Provides immunity to Curse of Darkness. Template:No unlocks
64 Template:Dlc
THRE
AD
Escape the labyrinth Provides immunity to Curse of the Labyrinth. Template:No unlocks
65 Template:Dlc
F0VN
D
I once was lost Provides immunity to Curse of the Lost. Template:No unlocks
66 Template:Dlc
N0W1
KN0W
Know the unknown Provides immunity to Curse of the Unknown. Template:No unlocks
67 Template:Dlc
PATH
F1ND
Stay out of the maze Provides immunity to Curse of the Maze. Template:No unlocks
68 Template:Dlc
BRA1
LLE
Heal the blind Provides immunity to Curse of the Blind. Template:No unlocks
70 Template:Dlc
BLCK
CNDL
Total curse immunity Provides immunity to all curses. Template:No unlocks
Damage Modifiers
47 HARD
HARD
Full heart damage Isaac takes a full heart of damage from all sources.
48 BRTL
B0NS
Twelve heart damage Isaac takes twelve hearts of damage from all sources.
26 D0NT
ST0P
Don't stop moving Isaac takes damage if he stops moving.
27 THEG
H0ST
Damage on a timer Every 45 seconds, a ticking will begin, and after 5 seconds, Isaac will take 1/2 heart of damage. Damage increases to 1 heart in Chapter 4 and beyond. Having invincibility during the time when damage should be inflicted blocks the damage.
28 30M1
N1TS
30 minute limit Gives a time limit of 30 minutes to beat the game. When the timer hits 29:45, a timer starts ticking, and after 30:00, Isaac takes damage every second.
Control Modifiers
52 Template:Dlc
1CES
KATE
Ice physics Makes the ground slippery.
74 Template:Dlc
BRAV
ERY
Bravery Isaac automatically fires tears in the same direction that he moves. Removes the ability to fire tears manually.
75 Template:Dlc
C0WR
D1CE
Cowardice Isaac automatically fires tears in the opposite direction that he moves. Removes the ability to fire tears manually.
12 DRAW
KCAB
Reversed controls All movement and firing keys are reversed.
76 Template:Dlc
AX1S
ALGN
Axis aligned controls Isaac cannot move diagonally.
Camouflage
3 CAM0
K1DD
Camouflage player Isaac blends into the ground.
4 CAM0
F0ES
Camouflage enemies All enemies blend into the ground.
5 CAM0
DR0P
Camouflage stuff Pickups and items blend into the ground.
6 WH0A
WHAT
Camouflage EVERYTHING! Isaac, enemies, pickups, and items all blend into the ground.
14 1MN0
B0DY
Invisible player Isaac becomes completely invisible.
15 BL1N
DEYE
Invisible enemies All enemies become completely invisible.
Player Appearance
46 THEB
LANK
The blank Isaac has no face.
53 KAPP
A
Grayscale Isaac turns gray.
54 H0H0
H0H0
Christmas Isaac wears a Christmas hat.
35 T0PH
EAVY
Big head mode Isaac's head is large.
36 T1NY
D0ME
Tiny head mode Isaac's head is small.
37 PTCH
BLCK
Black body Isaac and his tears turn completely black.
Visual Effects
38 TEAR
GL0W
Glowing tears Isaac's tears glow. Template:No unlocks
23 BL00
00DY
Extra gore Makes a lot more blood appear after enemies die.
HUD Modifiers
8 B00B
T00B
Cathode rays! Applies a filter that makes the game look like it's being played through a cathode ray tube.
9 DYSL
EX1A
Dyslexia All in-game text is rearranged.
10 KEEP
TRAK
No HUD Removes the HUD entirely. This affects the map, health, consumables, held items, pickup text, floor names, and more.
29 MED1
C1NE
Mystery pills All pill names and descriptions show ???.
30 FACE
D0WN
Mystery cards All card names and descriptions show ???.
Enemy Modifiers
13 CHAM
P10N
Champion enemies All enemies turn into champions if possible. Template:No unlocks
17 C0CK
FGHT
Charmed enemies All enemies are permanently charmed. Template:No unlocks
18 C0NF
ETT1
Confused enemies All enemies are permanently confused. Template:No unlocks
19 FEAR
M1NT
Scaredy enemies All enemies are permanently scared. Template:No unlocks
20 FRA1
DN0T
Skittish enemies Every few seconds, all enemies become scared. Template:No unlocks
21 CLST
RPH0
Asocial enemies All enemies are permanently charmed and scared. Template:No unlocks
Sound Modifiers
7 FART
SNDS
Farty sounds All sound effects are replaced with farts.
1 SL0W
4ME2
Movement tempo Music speed is affected by Isaac's walking speed.
2 HART
BEAT
Health tempo The lower Isaac's health is, the slower the music is.
41 ANDA
NTE
Downtempo Music is slowed down.
42 LARG
HET0
Downtempo-- Music is significantly slowed down.
43 ALLE
GR0
Uptempo Music is sped up.
44 PRES
T0
Uptempo++ Music is significantly sped up.
Video Games?
77 Template:Dlc
SVPE
RH0T
SuperHot While Isaac is not moving, time runs extremely slowly. Isaac's speed and fire rate remain normal at all times. Template:No unlocks
78 Template:Dlc
M0DE
SEVN
Retro vision Screen has a permanent Retro-Vision effect.

Notes Regarding Seed Effects[ | ]

  • While the BRTL B0NS seed is enabled, getting hit will not result in death if Isaac possesses Template:Es as well as Template:Es or Template:Es. Instead, the Soul hearts and/or Black hearts will be completely depleted, leaving Isaac with only his Red hearts. You can also prevent death with Template:Es, as they will get depleted without destroying the bone heart and protecting the rest of the hearts, and can be refilled with Red Hearts. The soul hearts in front of them will get destroyed though.
  • If the ICES KATE seed is enabled, purple champion monsters will be much more dangerous, as escaping their gravitational pull is almost impossible.
  • When playing with the KAPP A seed enabled, certain items will override the grayscale, such as Template:I.
  • When the seed PACI FISM is enabled, effects that kill enemies on impact such as Template:I and Template:I still remove enemies, but they will respawn when the room is re-entered. No effect occurs after killing all in a room.
  • Some seeds can not be enabled alongside other certain seeds. For example, the PTCH BLCK seed cannot be enabled alongside THEB LANK.
  • It is possible to access other chapters while playing the BASE MENT seed. Stepping into the beam of light after using Template:I can take Isaac to chapter II, avoiding the standard loop after the first two basement floors. Additionally, Template:Rs after 12 uses can be used at any point to teleport to the Template:S, making it possible to see a proper ending and finish the run.

Trivia[ | ]

  • Many of the special seeds can be found by using either the Template:M or the Template:P.
  • Some special seeds were shared with the community by the developers.
  • If an item that would appear on a seed isn't unlocked yet, it will be replaced by another item that is unlocked.
  • The "DYSL EXIA" seed is a reference to dyslexia, a disorder that causes difficulties in spelling, reading, and writing.
  • The seeds "ANDA NTE", "LARG HET0", "ALLE GR0", and "PRES T0" refer to andante, larghetto, allegro, and presto, respectively. These are names of musical tempos, which are the speeds of given pieces of music.
  • The "KAPP A" seed is a reference to a commonly used Twitch emote "KAPPA".
  • The "ALM1 GHTY" seed's description is, "Dog Mode". This is referencing the term "God mode", which is used to describe someone or something in a game that's invincible, usually through the use of cheats.
    • "Dog Mode" is also a reference to Rise of the Triad, which has a power-up of the same name.
  • The "FEAR M1NT" seed is a reference to spearmint, a popular chewing gum flavor.
  • Although the T1NY D0ME seed also makes Isaac's hitbox somewhat smaller and could be considered beneficial, it does not prevent achievements.
  • Template:Dlc The "SVPE RH0T" seed is a reference to the game SUPERHOT.
  • Template:Dlc "M0DE SEVN" i.e. Mode 7 is a graphics mode on the Super Nintendo Entertainment System console that often results in pronounced pixelation.
  • Template:Dlc"GFVE LLLL" is used as 11/4/2022's daily run.

Bugs[ | ]

Template:Bug Template:Bug Template:Bug

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