The Binding of Isaac Wiki
Advertisement

The Virus is a passive item.

A syringe with a red substance in it.

Effects

Isaac becomes pale with signs of sickness on his body, and gets bumps and markings.

Touching enemies will inflict them with poison, as well as deal a large amount of damage.

The Virus also decreases Speed by 0.1, however this reduction in speed does not stack with the speed down from Odd Mushroom (Large).

Synergies

  • Book Of Shadows - Turns you invincible with the poison touch effect still working while invincible.
  • The Polaroid - While invincible, allows Isaac to poison enemies without taking damage.
  • Celtic Cross - If invincibility triggers, poison touch will be effective against many enemies.
  • My Little Unicorn/The Gamekid - Poison touch overrides their 40 damage hit with its 30 damage hit (and poison). Otherwise it doesn't change what they do.
  • The Nail - The contact damage of The Virus overrides the contact damage of The Nail.
  • Mom's Bra/Mom's Pad - Contact damage on the player is disabled during the effect of either active. This allowing for safer application of the contact damage and poison damage of The Virus.
  • Best Friend - The brief window of invincibility frames when casting Best Friend allow for a free application of The Virus.

Trivia

  • The substance in the syringe is probably infected blood, which is an incredibly easy way to contract STDs.
  • Lust is a recolor of Isaac with The Virus graphic applied. Lust also has a chance to drop The Virus upon death.
    • This may be why it's thought to be an STD.

Bugs

  • The Virus, like all other contact damage items, cannot inflict contact damage or poison damage to Hearts or Mom's Heart/It Lives, but can do so to other enemies that don't deal contact damage to the player.

Related Achievements

Items
Passive Items
The Sad OnionThe Inner EyeSpoon BenderMax's HeadMy ReflectionNumber OneBlood of the MartyrBrother BobbySkatoleCube of Meat


Halo Of Flies1UPMagic MushroomThe VirusRoid RageLess Than ThreeRaw LiverSkeleton KeyA DollarA Quarter


Boom!TranscendenceThe CompassLunchDinnerDessertBreakfastRotten MeatWooden SpoonPHD


The BeltMom's UnderwearMom's HeelsMom's LipstickWire Coat HangerRosaryXRay VisionLucky FootCupid's ArrowSteven


PentagramDr. FetusMagnetoTreasure MapMom's EyeDistant AdmirationWiggle WormThe LadderCharm Of The VampireThe Mark


The BatterySteam SaleSister MaggyTechnologyChocolate MilkGrowth HormonesMini MushroomThe PactDead CatLord Of The Pit


Loki's HornsLittle ChubbySpider's BiteSmall RockSpelunker HatSuper BandageSack Of PenniesRobo-BabyLittle C.H.A.D.The Relic


Little GishLittle SteveThe HaloThe Common ColdThe ParasiteMr. MegaThe WaferMoney Equals PowerMom's ContactsGuardian Angel


Demon BabyMom's KnifeOuija Board9 VoltDead BirdBrimstoneBlood BagOdd Mushroom (Thin)Odd Mushroom (Large)Whore Of Babylon


Bobby-BombForever AloneBucket Of LardBomb BagA Lump of Coal


Wrath of the Lamb DLC.png


Guppy's TailStigmataMom's PurseBob's CursePageant BoyScapularSpeed BallBum FriendInfestationIPECAC


Tough LoveThe MulliganTechnology 2Mutant SpiderChemical PeelThe PeeperHabitBloody LustSpirit Of The NightAnkh


Celtic CrossGhost BabyCat-O-Nine-TailsHarlequin BabyEpic FetusPolyphemusDaddy LonglegsSacrificial DaggerMitreRainbow Baby


Stem CellsHoly WaterFateThe Black BeanSacred HeartTooth PicksHoly GrailDead DoveGuppy's Hair BallAbel


SMB Super Fan!Pyro3 Dollar BillMEAT!Magic 8 BallMom's Coin PurseSqueezyJesus JuiceBox
Activated Items
The BibleThe Book of BelialThe NecronomiconThe PoopMr. BoomTammy's HeadMom's BraKamikazeMom's PadBob's Rotten Head


Teleport!My Little UnicornYum HeartDoctor's RemoteShoop Da Whoop!Book Of RevelationsLemon MishapBook of ShadowsAnarchist CookbookThe Hourglass


The NailWe Need To Go Deeper!Deck of CardsMonstro's ToothThe GamekidThe Book Of SinMom's Bottle of PillsThe DiceThe Pinking ShearsThe Bean


Monster ManuelDead Sea ScrollsRazor BladeForget Me NowA Pony


Wrath of the Lamb DLC.png


Guppy's PawIV BagBest FriendRemote DetonatorGuppy's HeadPrayer CardNotched AxeCrystal BallCrack The SkyThe Candle


D20Spider ButtDad's KeyPortable SlotWhite PonyBlood RightsTelepathy for Dummies
Advertisement