The Binding of Isaac Wiki
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The Book of Sin is an unlockable activated item.

A black book with the number seven written in red ink on the cover, with some splotches around the seven.

Effects

Spawns one random Pick Up item (excluding Trinkets and Chests).

Possible drops:

Synergies

  • As with most activated items, items such as Habit, 9 Volt and The Battery decrease the charge time, increasing the effectiveness of this item.
  • Pill-related items such as PHD or Lucky Foot work well with this item, as they prevent the player from receiving negative pill effects.
  • Trinkets such as Bloody Penny, Burnt Penny, Flat Penny and Counterfeit Penny work well with this item, as picking up coins spawned by this item while holding any of these Trinkets give the chance of receiving an additional item.
  • You can farm pick ups from this item and Habit by using the Blood Donation Machine or a Demon Beggar. However, this is risky as this item does not always give Hearts, and the player could potentially lose more hearts than they started with. But the Blood Donation Machine could give you Blood Bag after a few attempts. (Or the less desirable IV Bag that does not give hearts)

Trivia

  • Some believe that each pickup represents one of the seven deadly sins:
    • Whole Heart: Gluttony
    • Bomb or bomb variant (1+1 Free, Troll Bomb, etc.): Wrath
    • Pills: Lust
    • Random Coin: Greed
    • Tarot Cards: Sloth
    • Soul Heart: Envy
    • Key: Pride
Items
Passive Items
The Sad OnionThe Inner EyeSpoon BenderMax's HeadMy ReflectionNumber OneBlood of the MartyrBrother BobbySkatoleCube of Meat


Halo Of Flies1UPMagic MushroomThe VirusRoid RageLess Than ThreeRaw LiverSkeleton KeyA DollarA Quarter


Boom!TranscendenceThe CompassLunchDinnerDessertBreakfastRotten MeatWooden SpoonPHD


The BeltMom's UnderwearMom's HeelsMom's LipstickWire Coat HangerRosaryXRay VisionLucky FootCupid's ArrowSteven


PentagramDr. FetusMagnetoTreasure MapMom's EyeDistant AdmirationWiggle WormThe LadderCharm Of The VampireThe Mark


The BatterySteam SaleSister MaggyTechnologyChocolate MilkGrowth HormonesMini MushroomThe PactDead CatLord Of The Pit


Loki's HornsLittle ChubbySpider's BiteSmall RockSpelunker HatSuper BandageSack Of PenniesRobo-BabyLittle C.H.A.D.The Relic


Little GishLittle SteveThe HaloThe Common ColdThe ParasiteMr. MegaThe WaferMoney Equals PowerMom's ContactsGuardian Angel


Demon BabyMom's KnifeOuija Board9 VoltDead BirdBrimstoneBlood BagOdd Mushroom (Thin)Odd Mushroom (Large)Whore Of Babylon


Bobby-BombForever AloneBucket Of LardBomb BagA Lump of Coal


Wrath of the Lamb DLC.png


Guppy's TailStigmataMom's PurseBob's CursePageant BoyScapularSpeed BallBum FriendInfestationIPECAC


Tough LoveThe MulliganTechnology 2Mutant SpiderChemical PeelThe PeeperHabitBloody LustSpirit Of The NightAnkh


Celtic CrossGhost BabyCat-O-Nine-TailsHarlequin BabyEpic FetusPolyphemusDaddy LonglegsSacrificial DaggerMitreRainbow Baby


Stem CellsHoly WaterFateThe Black BeanSacred HeartTooth PicksHoly GrailDead DoveGuppy's Hair BallAbel


SMB Super Fan!Pyro3 Dollar BillMEAT!Magic 8 BallMom's Coin PurseSqueezyJesus JuiceBox
Activated Items
The BibleThe Book of BelialThe NecronomiconThe PoopMr. BoomTammy's HeadMom's BraKamikazeMom's PadBob's Rotten Head


Teleport!My Little UnicornYum HeartDoctor's RemoteShoop Da Whoop!Book Of RevelationsLemon MishapBook of ShadowsAnarchist CookbookThe Hourglass


The NailWe Need To Go Deeper!Deck of CardsMonstro's ToothThe GamekidThe Book Of SinMom's Bottle of PillsThe DiceThe Pinking ShearsThe Bean


Monster ManuelDead Sea ScrollsRazor BladeForget Me NowA Pony


Wrath of the Lamb DLC.png


Guppy's PawIV BagBest FriendRemote DetonatorGuppy's HeadPrayer CardNotched AxeCrystal BallCrack The SkyThe Candle


D20Spider ButtDad's KeyPortable SlotWhite PonyBlood RightsTelepathy for Dummies
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