The Binding of Isaac Wiki
For other uses, see The Binding of Isaac (disambiguation).

The Binding of Isaac is a 3rd track from the original The Binding of Isaac soundtrack album. It is used for the game's main menu screen.

This song was not remixed for the Piano Collection album.


Coming soon.


  • In Rebirth, the music was replaced by a whole new track called "Genesis 22:10", which refers to the biblical verse of Abraham attempting his sacrifice for his own son Isaac. Later, the track was replaced by "ReGenesis" for the Afterbirth DLC, and finally "Genesis Retake Light" for the Repentance DLC.
The Binding of Isaac (OST)
Original Those ResponsibleIn The Beginning...The Binding of IsaacUnknown Depths BelowSacrificialConflictedDivine CombatPridePeace Be With YouAgonyRepentantRespite$4cR1f1c14|_DreadfulBurning AmbushGreedThine Wrath...ApostateHereafterTemptationThe Pact...Be DoneAbsolutionUltimate RewardEnd TimesIn The Beginning... (No Voiceover)The Clubbing of Isaac (Remix)C418 - AtempauseA Mourner Unto SheolEnmity of the Dark LordJesus Loves Me
Wrath of the Lamb PenanceAtonementLatter DaysLament of the AngelUnholy AssaultCrusadeSerenityTomesThe Wages of FaithMy Innermost Apocalypse
The Binding of Isaac: Rebirth (OST)
Original Genesis 22:10Diptera SonataCrusadeSodden HollowThe ForgottenAbyssMatricideThe CalmVisceraVentricideAcceptanceAnima VenditDuressHericideMurmur of the HarvestmanEmpty VesselsEverlasting HymnInfanticideAmbushTome of KnowledgePericulumCapiticus CalvariaWhen Blood DriesSketches of PainAscensionDevoidThe Fallen AngelTributeGenesis 13:37HushDescensumHe's the Number One
Afterbirth ReGenesisCerebrum DispersioCicatrixFundamentumKave DiluviiNativitateMoriturosPulso ProfundumChorus Mortis
Afterbirth † TerminusDeliriumSepulcrumAnte Lucem
The Legend of Bum-bo (OST)
SomnumStercus SonataDominusNickel GrinderFortitudoBeatitudineForlorn HollowMagnus DominusHalls of BelialTractusBum-Bo Got Coin!Vermis