The Binding of Isaac Wiki
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The Binding of Isaac has 113 Secrets (As of Eternal Edition v1.666) that can be unlocked. Secrets can add different kinds of things to the game, such as Items, Bosses, Characters, etc. They may have corresponding Achievements.

In-Game Secrets List

Basic Progression Unlocks

Character and Combo Unlocks

Game Completion Unlocks

Special Bosses and Loot

Separate Task Based

No Damage Achievements

Halloween Update

(Some of these may be wrong)

Wrath of the Lamb In-Game Secrets List

Characters

Game Completion Unlocks

The Chest

Challenges

Task Based

Eternal Edition In-Game Secrets List

The Chest

Task Based

Bugs

  • Secrets might be missing even though they have already been earned, due to various Anti-Virus programs, CCleaner (Or similar cleaner programs) or Steam's Cloud Sync.
    • For a detailed description on how to fix the missing secrets, check the video below.

Videos

The_Binding_of_Isaac_PSA_1_-_Missing_Secrets_Fix

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