- For other uses, see Worm (disambiguation).
The Nightcrawler is an enemy added to The Binding of Isaac: Rebirth. It is very similar to the Round Worm, but colored in deep indigo with a single eye.
It appear rarely somewhere in Chapter 1 and commonly in Chapter 2 and 3 respectively.
It attacks by shooting 4 shots that orbit around itself similar to the item Tiny Planet. It shoots a little faster and has more health than the Round Worm.
- A nightcrawler is an earthworm used as fish bait. They were scientifically known as "lumbricus terrestris".