Isaac RebirthKeeper sprite

Mom's Hand is a predictable but dangerous enemy. They were first added in The Binding of Isaac: Rebirth.

In the Afterbirth DLC, they can be encountered in Scarred Womb and the I AM ERROR secret room as well.


Mom's Hand telegraphs its presence by a distinct Mom's laugh upon entering the room. The hand(s) will then fall down from the ceiling and attempt to grab Isaac, dealing half a heart of damage in addition to sending Isaac to the previous room.

In the Afterbirth expansion, the ground may shake to signal Mom's Hand.


  • In the Afterbirth DLC, 1 or 2 Mom's Hand allies can be summoned when using Emergency Contact.


  • This enemy is likely a reference to the Wallmaster, an enemy encountered in The Legend of Zelda series.


  • Unlimited hearts: If Mom's hand is spawned in a room with any other hearts, specifically Soul or Black hearts, you can gain unlimited hearts. This is done by -
  1. Picking up the heart (+1 heart)
  2. Getting taken out of the room by Mom's hand (-0.5 heart)
  3. Repeat as necessary, gaining half a heart each time.
Black FlyAttack FlyMoterEternal FlyPooterFat FlyBoom FlyRed Boom FlyDrowned Boom FlySuckerSpitDart FlySwarm FlyRing FlyLevel 2 FlyFull FlyHush FlyBall of FliesSpiderBig SpiderTriteRaglingRag TriteLevel 2 SpiderTicking SpiderBaby Long LegsCrazy Long LegsWall CreepBlind CreepRage CreepPara-BiteCod WormScarred Para-BiteRound WormNightcrawlerRoundyUlcerMaggotChargerSpittyConjoined SpittyDrowned ChargerGrubClottyClotMega ClottyLeechKamikaze LeechHoly Leech
BoilGutSackBlue BoilHostRed HostWall HuggerSlidePokyStone GrimaceVomit GrimaceGaping MawTurret GrimaceBrimstone Grimace
MulliganMulligoonMulliboomHiveSwarmerNestDrowned HiveHopperFlaming HopperLeaperPacerGusherSplasherGaperFrowning GaperGurgleMr. MawFlaming GaperCyclopiaSkinnyRottyNullGreed GaperBlue GaperSwingerHorfPsychic HorfGlobinGazing GlobinBlack GlobinDank GlobinKnightSelfless KnightFloating KnightBone KnightBonyBlack BonyFattyFlaming FattyConjoined FattyBlue Conjoined FattyPale FattyKeeperHangerVisDouble VisChubberCage VisScarred Double VisHomunculusBegottenDopleEvil Twin
Body parts
Mask + HeartBrainMemBrainGutsMama GutsEyeBloodshot EyeMom's HandDead Mom's HandScarred GutsNerve EndingStone Eye
DipCorn DipBrown DipSquirtDank SquirtDinga
MawRed MawPsychic MawDeath's HeadDank Death's HeadFlesh Death's HeadLil' HauntWizoobRed GhostOne ToothFat BatTumorPsy TumorCamillo Jr.BabyAngelic BabyImpDukieOobBlack Maw
FredLumpEmbryoB. Licker
Community content is available under CC-BY-SA unless otherwise noted.