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Minor characters (also known as NPCs [Non-playable characters]) are characters in the series of The Binding of Isaac which were not directly played by Isaac or other playable characters.

The Binding of Isaac / Rebirth

Isaac's Mom

For the article about the boss, see Mom.

Issac's mother is the main antagonist of the game's prologue. She was asked by God to sacrifice her own son in order to ultimately prove her love and devotion, causing Issac to retreat to the basement. Isaac's mother, right when she is about to end her son's life in the name of faith, is stopped by divine intervention and Isaac's life is saved.

Isaac's Dad

Not much is known about Isaac's father but there are three photos of him seen during Ending 14. The last image of him is him leaving from Isaac's home. Isaac's father and Mom are assumed to be divorced because of the items Torn Photo, which has his father ripped out of the picture, and Divorce Papers.

His name was also mentioned from the item Dad's Key.

God

Coming soon.

Children from Isaac's thoughts

Coming soon.

Deceased residents

Coming soon.

Characters
The Binding of Isaac / Rebirth
Playable characters Original: IsaacMagdaleneJudasCainEve???
(Wrath of the Lamb: Samson)

Rebirth: AzazelEdenLazarusThe Lost
(Afterbirth: LilithKeeper • (Satoru Iwata))
(Afterbirth †: ApollyonThe Forgotten)

Beggars Original: BeggarShell Game Beggar
(Wrath of the Lamb: Devil Beggar)

Rebirth: Key Beggar
(Afterbirth: Bomb Bum)

Other NPCs Original: ShopkeeperOther characters
Rebirth: Babies
Unused Old Man Keeper (Rebirth)
The Legend of Bum-bo
Playable characters Bum-bo the BraveBum-bo the NimbleBum-bo the StoutBum-bo the WeirdBum-bo the DeadBum-bo the Empty
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