Isaac RebirthKeeper sprite

Mega Maw is a new boss added in The Binding of Isaac: Rebirth. Its design is based of the Psychic Maw.


He is a larger version of the Psychic Maw enemy with huge, empty eye-sockets. It has blood running from its eye-sockets as well as from its jaw. There is a long slit from its forehead which can open while shooting projectiles.


The Mega Maw will stay in the top of the room and will not follow the player. Its attacks are:

  • Monstro-like blood shots
  • A ring of fast purple flames
  • A spinning ring of slower purple flames
  • Two spinning rings of purple flames (less dense than previous attacks)
  • Summoning Hoppers


  • Despite being based off of the Psychic Maw, it doesn't shoot homing tears or any kind of homing projectile.
  • Mom's Knife and Ludvico Technique can be really useful in this boss, as it stays still during all the fight. The player will only have to worry about dodging its attacks.


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Regular Bosses
BlastocystChubDaddy Long LegsDark OneDingleDuke of FliesThe FallenFistulaGeminiGurdyGurdy Jr.GurglingsThe HauntLarry Jr.LokiMama GurdyMask of InfamyMega FattyMega MawMonstroMr. FredPeepPinPolycephalusScolexTurdlingsWidow

Afterbirth: BrownieDangleLittle HornRag ManTurdlings
Afterbirth †: Big HornRag Mega
Antibirth-only: Baby PlumBeelzeblubChimeraGreat GideonHornfelThe RainmakerReap CreepRotgutThe ScourgeThe SirenTuff TwinsWormwood

Posthumous Bosses
The AdversaryThe Blighted OvumThe BloatThe CageCarrion QueenThe GateThe HollowThe HuskLokiiMonstro IITeratomaThe Wretched

Afterbirth: The ForsakenThe FrailThe Stain
Antibirth-only: The HereticThe PileThe Visage

Alternative Bosses

Afterbirth †: Sisters Vis

ConquestWarFamineDeathPestilenceHeadless Horseman
Final Bosses
???IsaacIt LivesThe LambMega SatanMomMom's HeartSatan

Afterbirth: HushUltra Greed
Afterbirth †: Delirium
Antibirth-only: The Witness

Seven Deadly Sins
Seven Super Deadly Sins
Super EnvySuper GluttonySuper GreedSuper LustSuper PrideSuper SlothSuper WrathUltra Pride
Angels / Demons
KrampusGabrielUrielFallen Angels
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