Loki's Horns is an unlockable passive item.
It appears as two small horns, similar to the ones of Loki.
Gives Isaac Loki's horns and grants a 1/8 chance for tears to fire in a cross (+) pattern. The chance is increasing to 9/16 with Mom's Eye and to 100% with Mom's Eye and The Inner Eye. The Inner Eye without Mom's Eye does not affect the chance. This chance is increased with Isaac's Tears stat.
- If the player shoots a charged Chocolate Milk shot, all of the cross pattern shots will be charged.
- Mom's Eye and The Inner Eye - The cross pattern shot is always fired.
- This does not work with Mutant Spider despite its similarities with The Inner Eye.
- Brimstone - When the cross pattern is shot instead of lasers firing in each direction it shoots the laser and shoots tears in the other directions that have the original damage of the tears before being altered by Brimstone.
- Mom's Knife - The player is surrounded by four knives. Can't fire the extra knives, but they all deal contact damage.
- Sometimes it may appear before being unlocked.