Karma is an unlockable trinket added in The Binding of Isaac: Afterbirth.
- When Isaac donates to the Donation Machine, gives a chance to heal him for a red heart or spawn a Beggar.
- Increases the chance of increasing Isaac's luck when he donates to the Donation Machine.
- The icon of Karma is a triple spiral. This is one of the main symbols of Celtic Reconstructionism, and also sometimes used as the Christian Trinity symbol.
- This symbol can be found also in the Trinity Shield.
- In the Booster Pack #5, the icon was updated. But its achievement icon was not and still using the old version of Karma.
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