The Binding of Isaac Wiki

Items are an integral part of gameplay in The Binding of Isaac. They modify a character's stats, grant or modify abilities, and many other things.

Items in general are classified into a number of distinct types and groups. Some items are passive, which add an effect permanently to Isaac, while others only activate when used.

Items dropped in the Binding of Isaac NEVER disappear over time; a coin dropped will remain where it was dropped until you pick it up or leave the floor. A dropped item can be left in its place to be collected at a later time.


Among these types are:

Activated Items[]

Activated Items fill your spacebar slot. Only one can be carried at a time. An activated item can be used by pressing space, and unlike a pill or card, activated items recharge over time and can be reused when ready. Each item has a unique effect. Most activated items can only appear once per game with few exceptions, so leaving behind an activated item is typically a permanent choice.


These Items, when picked up, add a permanent effect to Isaac. These cannot be removed and are individually counted on the collection screen. Collectible items can be obtained in a variety of ways and most are unique in that, once appearing in game, they will never appear again during that session.


These go into your Q slot and are one-time-use items. There are a number of different pill styles and effects. At the start of the game, each type is randomly assigned an effect, which remains bound to that pill style for the remainder of that game. Pills start unidentified and are identified once used, unless the player has the PHD item, which identifies pills after a short delay. Picking up a pill or card while you already have one causes the old one to be dropped.

Tarot Cards[]

Tarot Cards are also Q slot items, and are also one-time use. Tarot Cards are unidentified when dropped and immediately identified when picked up. Each card has a unique and pre-determined effect. Picking up a pill or card while already carrying one causes the old one to be dropped.


Trinkets fill their own slot and are passive items that affect Isaac in unique ways. Only one can be carried at a time (Unless the player has Mom's Purse, which allows Isaac to hold two Trinkets at once); taking another will replace the current trinket and drop the old one.

Pick Ups[]

These are common items dropped in game and, when taken automatically confer their effect. This category includes items such as coins, hearts, keys and bombs and disappear once picked up.


Collectibles (a.k.a. Pedestal Items) is what Active & Passive items are together. They're the items that will (almost) always spawn on top of a Pedestal, and will add to your run for a longer and more notable amount of time than Pickups or Cards/Pills, Passive items specifically being permanent, and Actives being an integral part of the run, whether they're used for killing or not.

There are multiple ways of obtaining Pedestal Items, such as the following:

  1. Inside of Treasure Rooms.
  2. In Shops, bought for Pennies.
  3. Given to the player in Boss Rooms, after beating their respective Boss.
  4. Rarely inside Golden Chests, mostly after clearing a room, inside Tinted Rocks, or in Challenge Rooms.
  5. Inside Boss Challenge Rooms.
  6. Sitting in Libraries (books only).
  7. In Devil Rooms, traded for Heart Containers.
  8. Gifted in Angel Rooms.
  9. In certain layouts of Secret Rooms.
  10. Rarely in Curse Rooms.
  11. In Arcades.

All these methods will give different items, depending on the Item Pool they pull from. For example, you will never find items from the Treasure Room in an Angel Room.

There are 198 different collectible items in the game. Below is a list of all of the collectibles, separated into categories. Certain collectibles change the appearance of your character when they are acquired. Collectibles you've found can be seen in the Collection page.

Activated Collectibles[]

These items are stored in the Spacebar slot and are used up once the button is pressed. The items then recharge in one of two ways. Normally, they charge a number of bars after every room you clear—some items charge one bar at a time, others charge faster. Note that only rooms where the doors close until they are cleared count—Bosses, arenas, enemy rooms, etc. The Collectible Item "Battery" can give bars of charge during combat, on top of the normal recharge. Another Collectible Item, the "9 Volt", will automatically recharge 2 bars when an item is used; this effectively reduces the number of rooms required to charge an item if the item requires 3 or more rooms to charge. In the Wrath of the Lamb DLC, there is another item, the Habit, which will recharge bars when taking damage. To see a clearer version of the in-game arrangement, go to the Collection page.

Unlike Passive Collectibles, these are not permanent and can be easily interchanged for others, similar to Trinkets.

Note: Any two of the same activated item on the same floor will share charge state, i.e. Finding another of the same activated item when one is not fully charged will not give the player another fully charged version of the item. This can be observed in the Library, which can spawn 2 of the same book.

Item Icon Effect Recharge Time
Anarchist Cookbook Anarchist Cookbook Icon

Spawns six troll bombs around the room.

The Bean The Bean Icon

Causes Isaac to have bad gas, poisoning any enemy in close vicinity.

Bob's Rotten Head Bobs Rotten Head Icon

Throws a bomb in the direction Isaac's facing. It does extreme damage, poisons the enemy for 5 seconds, and destroys rocks.

The Bible The Bible Icon

Upon activation, Isaac gains Flight, allowing him to pass over all obstacles in the current room. Instantly kills Mom, Mom's Heart and It Lives when activated, will kill Isaac when activated while fighting Satan, Isaac or ??? unless he has The Wafer.

The Book Of Belial The Book Of Belial Icon

Adds 2 points of damage for the current room. Damage is further multiplied by 1.5x with the Blood Of The Martyr item. Also increases chances of a Devil Room spawning by 25%.

Book Of Revelations Book Of Revelations Icon

Adds 1 Soul Heart and makes the next boss a Horseman (except on XL Floors and on floors with fixed bosses such as Mom). Increases chances of a Devil Room spawning by 35%.

Book Of Shadows Book Of Shadows Icon

Grants Isaac invulnerability for 10 seconds.

The Book Of Sin The Book Of Sin Icon

Spawns a random Pick Up, Pill or Card.

Dead Sea Scrolls Dead Sea Scrolls Icon

Uses a random Activated Item.

Deck of Cards Deck Of Cards Icon

Gives Isaac a random Tarot Card.

The Dice The Dice Icon

Allows Isaac to re-roll collectible items in the current room into other items, depending on the current room's Item Pool.

Doctor's Remote Doctors Remote Icon

Sets a big red target on the ground (similar to the Epic Fetus item) which can be controlled with the arrow keys or the mouse. After 6 seconds or by pressing space again, a huge explosive missile hits it, which damages all enemies caught in its blast radius.

Forget Me Now Forget Me Now Icon

When activated, the level ends and is freshly regenerated with new rooms, monsters, and items. Disappears after use.

One-time use
The Gamekid The Gamekid Icon

Isaac turns into a Pac-Man-like creature for 5 seconds, gaining invincibility, +0.28 Speed, and the ability to damage enemies by touch, restoring a half-heart of health for every 2 enemies killed. Enemies will also turn blue and start fleeing from Isaac for the duration of the effect.

The Hourglass The Hourglass Icon

Upon activation, enemies and their projectiles are slowed down for 7.67 seconds.

Kamikaze! Kamikaze Icon

Creates an explosion in the same area as Isaac, dealing one heart of damage to him and also damaging all enemies caught in the blast radius.

Lemon Mishap Lemon Mishap Icon

Creates a small yellow pool of Creep, which damages enemies that cross it.

Mom's Bottle Of Pills Moms Bottle Of Pills Icon

Gives Isaac a random Pill, and will cause him to drop any held Q-slot item (If any). The player will only receive six different pill types in one playthrough.

Mom's Bra Moms Bra Icon

Causes Isaac to wear a bra on his head for a short period of time, which freezes enemies for 5 seconds.

Mom's Pad Moms Pad Icon

Causes enemies to back away from Isaac for 5 seconds.

Monster Manuel Monster Manuel Icon

Summons a random familiar for the current room only, even if it is locked.

Monstro's Tooth Monstros Tooth Icon

Monstro jumps onto a random enemy, doing damage. Cannot be used in a fight against Monstro, but can be used against Monstro II.

Mr. Boom Mr Boom Icon

Drops a large bomb.

My Little Unicorn My Little Unicorn Icon

Grants Isaac invincibility for a short period of time. Isaac cannot fire tears during the invincibility effect, but he can damage enemies by touch. Increases Speed by 0.28 for the duration of the effect.

The Nail The Nail Icon

On activation, adds one Soul Heart and allows the breaking of Rocks and damaging enemies by simply walking over them.

Increases Damage by 0.7 and decreases Speed by 0.18 for current room.

The Necronomicon The Necronomicon Icon

Damages all enemies in the room significantly.

A Pony A Pony Icon

Upon use, Isaac will charge in the direction selected, and will become invincible during the charge, allowing him to damage enemies by touch.
While equipped, passively increases Speed to a minimum of 1.5, and grants Isaac Flight.

The Poop The Poop Icon

Drops a pile of poop at his current location. This pile of poop may yield Hearts or Coins like regular poop.

Razor Blade Razor Blade Icon

Deals 1 Heart of damage to Isaac, which increases damage for the current room.

The Pinking Shears The Pinking Shears Icon

Separates Isaac's head and body for the current room. Isaac's head will be controlled, which now has Flight, while his body will seek out enemies to attack by contact damage.

Shoop Da Whoop! Shoop Da Whoop Icon

Fires a laser from Isaac's mouth.

Tammy's Head Tammys Head Icon

Shoots 10 tears in a circle around Isaac, which retain the size (damage), shot speed, and special effects (such as Poison) of Isaac's tears. The tears are not affected by tear-replacing items like Brimstone.

Teleport! Teleport Icon

Teleports Isaac to a random room on the current floor.

We Need To Go Deeper! We Need To Go Deeper Icon

Creates a trapdoor to go to the next floor. If used in The Womb, it will create a trapdoor to Sheol, even if the player hasn't unlocked it.
Does not work in Sheol, The Cathedral, or The Chest.

Yum Heart Yum Heart Icon

Restores 1 whole heart.


Wrath of the Lamb Activated CollectiblesWrath of the Lamb DLC[]

The following activated items can only be acquired in the Wrath of the Lamb DLC.

Item Icon Effect Recharge Time

Best Friend

Best Friend Icon

Deploys a decoy Isaac that eventually explodes with an increased blast radius.

Like all explosive attacks, the explosion can hurt Isaac if he is within the blast radius.

Blood Rights Blood Rights Icon

Deals a half-heart of damage to Isaac, which damages all enemies in the room.


The Candle

The Candle Icon

Throws out a blue flame that can pass over gaps (but not through rocks) that damages anything in its path.

Recharges 3 seconds after firing.

Recharges itself

Crack The Sky

Crack The Sky Icon

Summons multiple beams of light in random locations around the room, dealing a large amount of damage to any enemy that touches them.

Crystal Ball Crystal Ball Icon

Reveals the map and drops a random Tarot Card or Soul Heart.



D20 Icon

Randomly changes all Pick Ups in the current room.


Dad's Key

Dads Key Icon

Opens all doors in the current room when activated, except rooms which require a Key to open, such as Treasure Rooms and Libraries.


Guppy's Head

Guppyshead 1

Spawns 2-4 Blue Flies to damage enemies.


Guppy's Paw

Guppys Paw Icon

Removes one Heart Container in exchange for gaining 3 Soul Hearts.


IV Bag

IV Bag Icon

Upon activation, Isaac loses a half-heart (one whole heart in The Womb and onwards) for a random amount of coins, similar to the Blood Donation Machine.


Notched Axe

Notched Axe Icon

Breaks a single rock when activated.


Portable Slot

Portable Slot Icon

Upon activation, 1 coin will be consumed, and a random Pick Up may drop, similar to the Slot Machine.


Prayer Card

Prayer Card Icon

Grants half an Eternal Heart per use.


Remote Detonator

Remote Detonator Icon

Bombs you place explode only when you use this item.

Gives 5 bombs.


Spider Butt

Spider Butt Icon

Damages all enemies in the room and and slows them and their projectiles down for 2.5 seconds (similar to The Hourglass).


Telepathy For Dummies

Telepathy For Dummies Icon

Gives Isaac homing tears for the current room. (Identical to Spoon Bender)


White Pony

White Pony Icon

Upon use, Isaac will become invincible and charge in the direction selected, dealing damage to monsters touched. In addition, beams of light (similar to Crack The Sky) drop down in random locations around the room, damaging any enemies that touch them.

While equipped, increases Speed up to a minimum of 1.5, and grants Isaac Flight.


Passive Collectibles[]

These items generally give you some kind of a boost to your stats, or add a special passive ability. They take effect immediately once picked up, and continue for the rest of the game (except for several items that do not provide any lasting effect).

Edmund McMillen split them up in his blog into the subcategories "weapon items" (Such as Number One), "stat padding items" (Such as Growth Hormones), "passive items" (Such as Mitre), and Familiars (Such as Little Gish).

Item Icon Effect


Less Than Three Icon

Increases available heart containers by 1 and restores all health.


1 UP Icon

Gives an extra life. Upon death, you will respawn in the previous room with full health and lose the 1UP.

9 Volt

9 Volt Icon

Leaves Isaac with two bars already charged after using an item.

Upon pickup, Isaac's current activated item will be fully charged.

The Battery

The Battery Icon

Gives Isaac an extra charge every 15 seconds per room, up to a maximum of 3 charges.

The Belt

The Belt Icon

Increases Speed by 2.

Blood Bag

Blood Bag Icon

Increases HP by 1, Speed by 0.3, and restores 4 hearts.

More than one can be obtained during a same playthrough

Blood Of The Martyr

Blood Of The Martyr Icon

Increases Damage by 1, and turns Isaac's tears into blood tears. If collected with the The Book of Belial, damage will also be multiplied by 1.5x upon activation.


Bobby-Bomb Icon

Gives Isaac 5 Bombs, and causes all dropped bombs to home towards the closest enemy.

Bomb Bag

Bomb Bag Icon

Isaac is followed by a small bag that drops a Bomb, 1+1 Free, or a Troll Bomb every 3 rooms.


Boom Icon

Gives 10 bombs.


Breakfast Icon

Increases HP by 1.


Brimstone Icon

Changes tears to a chargeable laser, which pierces all objects in its path. Also multiplies damage by 3.

It can only be fired after a short charge-up period.

Brother Bobby

Brother Bobby Icon

Follows Isaac around shooting normal tears.

Bucket Of Lard

Bucket Of Lard Icon

Gives two empty heart containers, heals by half a heart but decreases speed by 1.

Charm Of The Vampire

Charm Of The Vampire Icon

Killing 13 monsters heals the player for half a heart.

Chocolate Milk

Chocolate Milk Icon

Allows Isaac to charge shots, making them a lot stronger and larger, and turns them brown. Tears will no longer automatically fire while holding down arrow keys.

The Common Cold

The Common Cold Icon

Gives Isaac's shot a chance of poisoning enemies for a 2.5 seconds, and turns tears green.

The Compass

The Compass Icon

Reveals all special rooms (Boss Rooms, Treasure Rooms, Shops, etc.), but not Secret Rooms/Super Secret Rooms or regular rooms.

Cube Of Meat Cube Of Meat Icon

The first pick up gives a floating cube similar to a Pretty Fly that damages enemies and blocks shots.

The second pick up changes it into a floating head that shoots red tears and blocks shots.

The third pick up changes it into a humanoid Meat Boy, who walks around chasing enemies, but no longer shoot projectiles.
(This stage and the last stage can push bombs around, which can damage Isaac if the player is not careful)

The fourth pick up increases his size and damage.

A fifth pick up will create another cube of meat orbital which then advances to another Super Meat Boy. However, it is not possible to have three or more Meat Boys, as the ninth cube will simply disappear on pickup.


Cupid's Arrow

Cupids Arrow Icon

Gives Isaac piercing tears that can travel through enemies. Removes knockback effect of tears.

Dead Bird

Dead Bird Icon

Whenever Isaac takes damage, the bird starts attacking nearby enemies while flying over obstacles. The effect only lasts for the current room.

Dead Cat

Dead Cat Icon

Your HP is set to 1.

You are followed by a floating cat head and have 9 lives (these still count as deaths on the statistics screen).

You can increase your max HP as normal, but after each death it will reset to 1 again.


Dessert Icon

Increases available heart containers by 1.


Dinner Icon

Increases available heart containers by 1.

Distant Admiration

Distant Admiration Icon

A red attack fly circles further out than the Halo of Flies/Pretty Flies, but closer than Forever Alone.

Deals more damage than Forever Alone.

Demon Baby

Demon Baby Icon

Follows Isaac and automatically fires at enemies in its reach.

A Dollar

A Dollar Icon

Gives Isaac 99 coins.
Can be found multiple times in a single playthrough.

Dr. Fetus

Dr Fetus Icon

Replaces Isaac's shot with a bomb.

Only one bomb can be shot at a time, and it will slide a fixed range before exploding.

Forever Alone

Forever Alone Icon

Spawns a blue attack fly that orbits a long distance from Isaac.

Growth Hormones

Growth Hormones Icon

Increase Speed and Damage by 2 each.

Guardian Angel

Guardian Angel Icon

Spawns a Guardian Angel that orbits Isaac.

Does damage on touch, blocks shots and doubles the speed of other orbitals.

The Halo

The Halo Icon

Increases all stats (Including Heart Containers) by one.

Halo Of Flies

Halo Of Flies Icon

Grants 2 Fly orbitals that circle Isaac.

Blocks shots and damages Fly enemies on touch.

The Inner Eye

The Inner Eye Icon

Gives Isaac a triple shot, sets Tears to minimum

The Ladder

The Ladder Icon

Allows Isaac to walk across gaps one square across by automatically placing a ladder between the two walkables.

Little C.H.A.D.

Little CHAD Icon

Isaac is followed by Little C.H.A.D, who will drop a half Heart every 2 rooms.

Little Chubby

Little Chubby Icon

Adds a small grub that follows Isaac.

Charges forward and deals touch damage to any enemies in her path. Will attack when the Isaac attacks with a moderate cooldown time before she can attack again.

Little Gish

Little Gish Icon

Follows Isaac around shooting tar projectiles that reduce enemies' movement speed, shot speed, and range for a few seconds.

Little Steve

Little Steve Icon

Follows Isaac around, shooting homing projectiles.

Loki's Horns

Lokis Horns Icon

Gives a random chance for projectiles to fire in a cross (+) pattern.

Lord Of The Pit

Lord Of The Pit Icon

Isaac can fly over all obstacles, including damage floors, spikes, rocks, and pits. Increases speed by 1.

Lucky Foot

Lucky Foot Icon

All Pills picked up will have positive or neutral effects (same effect as the PHD, but without pill identification and neutral pills). Increases the chance of getting Pick Ups from clearing a room or from Poop and Fireplaces. Increases the chance of winning the Shell game in the Arcade room from 33% to roughly 50%. Increases the chances of getting items from Golden Chests.


Lunch Icon

Increases available heart containers by 1.

A Lump Of Coal

A Lump Of Coal Icon

Increases damage of tears based on amount of time in the air. 0.14 damage per frame, or 4.2 damage per second.(tear size increases as it gets further away).

Magic Mushroom

Magic Mushroom Icon

Fully heals Isaac, increases all Stats (excluding Rate Of Fire) by 1, and multiplies damage by 1.5x.


Magneto Icon

Pulls Pick Ups towards Isaac.

The Mark

The Mark Icon

Increases Damage by 1, Speed by 0.2, and adds one Soul Heart.

Max's Head

Maxs Head Icon

Increases damage by 1, and multiplies it by 1.5x.

Mini Mushroom

Mini Mushroom Icon

Increases Speed and Range by 1.

Mom's Contacts

Moms Contacts Icon

Gives Isaac a petrifying shot that will randomly freeze enemies solid for a few seconds.

Mom's Eye

Moms Eye Icon

Allows Isaac to fire tears from the back of his head.

Mom's Heels

Moms Heels Icon

Increases Range by 7.75.

Mom's Knife

Moms Knife Icon

Once collected, Isaac no longer shoots tears, he shoots a knife in boomerang style. The range of throw increases by charging the shot.

Can also be used as a melee weapon while not fired.

Mom's Lipstick

Moms Lipstick Icon

Increases Range by 7.75.

Mom's Underwear

Moms Underwear Icon

Increases Range by 7.75.

Money = Power

Money Equals Power Icon

Increases damage based on the number of coins the player has at the moment.

Mr. Mega

Mr Mega Icon

Gives Isaac 5 bombs, and makes all dropped bombs larger (Similar to the bomb dropped by Mr. Boom), which have an increased blast radius and increased damage.

My Reflection

My Reflection Icon

Gives Isaac's tears a boomerang effect, and sets range to default.

Number One

Number One Icon

Sets Isaac's tears to their maximum rate of fire and minimum range.

Odd Mushroom (Large)

Odd Mushroom (Large) Icon

Increases damage by 0.3, adds an empty Heart Container, increases range by 2.75 and reduces Speed by 0.1.

Odd Mushroom (Thin)

Odd Mushroom (Thin) Icon

Increases Speed by 1, sets Rate Of Fire to maximum while reducing Damage by 1.

Ouija Board

Ouija Board Icon

Turns Isaac's tears spectral, allowing them to go through rocks or obstacles.

The Pact The Pact Icon

Increases Damage by 0.5 and Rate Of Fire by 0.7. The player also gains 2 Soul Hearts.

The Parasite

The Parasite Icon

Makes the Isaac's tears split in two when they hit something.


Pentagram Icon

Increases Damage by 1 and increases chances of the Devil Room appearing by 20%..


PHD Icon

Changes negative Pill effects into positive ones. Also causes Blood Donation Machines to drop more money. Restores 2 hearts upon pickup.

A Quarter

A Quarter Icon

Gives you 25 pennies.

Raw Liver

Raw Liver Icon

Increases available Heart Containers by 2 and completely restores health.

The Relic

The Relic Icon

Isaac is followed by a small blue cross that will drop a Soul Heart every 5 rooms.


Robo-Baby Icon

Follows Isaac around, shooting enemies with an eye laser similar to Technology.

Roid Rage

Roid Rage Icon

Increases Speed by 0.6. Does NOT increase range.


Rosary Icon

Adds 3 Soul Hearts and increases the chance for The Bible to appear in the Shop.

Rotten Meat

Rotten Meat Icon

Increases available heart containers by 1.

Sack Of Pennies

Sack Of Pennies Icon

Isaac is followed by a small bag that drops a coin every 2 rooms.
Usually a penny, sometimes a nickel.

The Sad Onion

The Sad Onion Icon

Increases tears by 0.7.

Sister Maggy

Sister Maggy Icon

Follows Isaac around shooting blood tears.


Skatatole Icon

All the various fly type enemies no longer harm you, shoot, or split.

Skeleton Key

Skeleton Key Icon

Sets your key count to the maximum of 99.

The Small Rock

Small Rock Icon

Increases damage by 1, increases tears by 0.2, decreases speed by 0.2.

Spelunker Hat

Spelunker Hat Icon

Reveals the Secret Room and Top Secret Room when passing by it and reveals if a room contains a mini-boss.

Spider's Bite

Spiders Bite Icon

Gives Isaac's shots a chance of slowing enemies for 2.5 seconds.

Spoon Bender

Spoon Bender Icon

Gives Isaac's shots the ability to curve towards enemies.

Steam Sale

Steam Sale Icon

Reduces all Shop prices by 50%, rounded down when an item, rounded up when a pickup.


Steven Icon

Increases Damage by 1.

Super Bandage

Super Bandage Icon

Increases HP by 1 and gives 2 soul hearts.


Technology Icon

Gives Isaac a laser shot with unlimited range.

Shots pierce enemies but not rocks, fire, or poop.

Shots can't be angled, and will not provide knockback.


Transcendence Icon

Removes Isaac's body, allowing flight over obstacles, spikes and pits.

Treasure Map

Treasure Map Icon

Reveals all rooms for every floor, including the Secret Room. However, it does not reveal icons.

The Virus

The Virus Icon

Isaac will automatically poison any enemy that he touches.

The Wafer

The Wafer Icon

Turns all types of damage into a half-heart, including damage taken in The Womb and onwards.

Whore Of Babylon

Whore Of Babylon Icon

When Isaac reaches a half-heart, he is given +2.16 damage, and his speed increases by 0.3.

Wiggle Worm

Wiggle Worm Icon

Gives Isaac waving shots and increases Rate Of Fire by 0.4.

Wire Coat Hanger

Wire Coat Hanger Icon

Increases Tears by 0.7.

Wooden Spoon

Wooden Spoon Icon

Increases speed by 0.3.

XRay Vision

XRay-Vision Icon

Reveals and opens Secret Room entrances.

Wrath of the Lamb Passive CollectiblesWrath of the Lamb DLC[]

The following collectible items can only be acquired if you have the Wrath of the Lamb DLC.

Item Icon Effect

3 Dollar Bill

3 Dollar Bill Icon

Effect given changes every room.


Abel Icon

Mirrors Isaac's movements. Shoots in opposite direction to the player.


Ankh Icon

When killed, respawns in the previous room as ???, regardless of the fact he is unlocked or not.

After respawn, all future HP upgrades will be soul hearts only. Only works once.

The Black Bean

The Black Bean Icon

When taking damage, Isaac farts, causing poison damage to all enemies in range.

Bloody Lust

Bloody Lust Icon

Increases damage each time Isaac kills an enemy for the current room. (.28 damage per kill, caps at 3.3.)

Bob's Curse

Bobs Curse Icon

Gives 5 bombs and grants all bombs poison effect.


Box Icon

Spawns 1 of each item: 1 coin, 1 key, 1 bomb, 1 heart, 1 card, 1 pill, 1 trinket.

Bum Friend

Bum Friend Icon

A portable Beggar who follows Isaac, pick up coins for himself, and occasionally drop Pick Ups. Does not spawn Collectibles. Can push around dropped bombs, similar to Meat Boy.


Cat-O-Nine-Tails Icon

Increases Shot Speed by 23%.

Celtic Cross

Celtic Cross Icon

Has a 20% to create a protective shield around Isaac upon taking damage, which grants him invulnerability to all forms of damage for 7 seconds.

Chemical Peel

Chemical Peel Icon

Tears fired from left eye do increased damage.

Daddy's Love

Daddy Longlegs Icon

Daddy Long Legs' shadow follows Isaac and stomps on enemies.

Dead Dove

Dead Dove Icon

Gives Isaac spectral tears and flight.

Epic Fetus

Epic Fetus Icon

Tears become guided missiles (See Doctor's Remote).


Fate Icon

Isaac gains flight and an Eternal Heart.

Ghost Baby

Ghost Baby Icon

Familiar that shoots spectral tears.

Guppy's Hair Ball

Guppys Hair Ball Icon

Loosely follows behind Isaac. Can be swung like a flail by rapidly spinning Isaac in a circle.

Grows bigger by killing enemies

Guppy's Tail

Guppys Tail Icon

Increases chance of gold chests and normal chests.


Habit Icon

When Isaac is hit, 3 points of an item's charge are filled.

Harlequin Baby

Harlequin Baby Icon

Familiar that shoots a pair of tears diagonally every second while Isaac is firing.

Holy Grail

Holy Grail Icon

Adds 1 empty heart container and gives flying ability.

Holy Water

Holy Water Icon

When Isaac receives damage, the bottle breaks and a puddle of blue Creep forms, which damages non-flying enemies, similar to Lemon Mishap.

The bottle is reformed upon entering a different room.


Infestation Icon

1-3 Blue Flies randomly spawn every time Isaac gets hit.



Green projectiles fired from the mouth causing poison/explosive damage.

Jesus Juice

Jesus Juice Icon

Increases Damage by 0.5 and increases Range.

Magic 8 Ball

Magic 8 Ball Icon

Increases Shot Speed.

Drops a Tarot Card when picked up.



Adds a heart container, and increases damage.


Mitre Icon

Greatly increases the chance of replacing spawned hearts with soul hearts.

Mom's Coin Purse

Moms Coin Purse Icon

Spawns 4 random Pills around Isaac.

Mom's Purse

Moms Purse Icon

Allows Isaac to hold 1 additional trinket.

The Mulligan

The Mulligan Icon

Chance to spawn Blue Flies on successful hits, which charge current target.

Mutant Spider

Mutant Spider Icon

Shoot four tears at once, greatly reduces tear firing rate.

Pageant Boy

Pageant Boy Icon

Spawns several coins around Isaac.

The Peeper

The Peeper Icon

Gives Isaac a familiar eye that floats around the room, damaging enemies on contact

Tears fired from left eye become red (cosmetic only)


Polyphemus Icon

Makes Isaac shoot one huge tear. Also reduces Tears to minimum. Damage increased by 4 and then multiplied by 2.

If tear does more damage than an enemy's life, the tear continues to travel with the extra remaining damage.


Pyro Icon

Adds 99 Bombs.

Rainbow Baby

Rainbow Baby Icon

Tear Effect changes every shot.

Sacred Heart

Sacred Heart Icon

Shots are larger, travel slower and home in on enemies. Damage is multiplied. (Multiplies damage by X2.3+1, -0.4 tears, -0.25 shot speed.)

Gives 1 Soul Heart and restores full Health on Pick up.

Sacrificial Dagger

Sacrificial Dagger Icon

Dagger orbits Isaac, very high damage.


Scapular Icon

Once per room, when Isaac is reduced to his last half red Heart, the aura around his head temporarily vanishes and he is granted one Soul Heart.

SMB Super Fan!

SMB Super Fan Icon

Increases all stats except Speed by 1. Reduces Speed by 1.

Speed Ball

Speed Ball Icon

Increases movement speed and causes tears to travel faster.

Spirit Of The Night

Spirit Of The Night Icon

Grants Isaac flight and spectral tears.


Squeezy Icon

+1 tears and spawns 2 soul hearts.

Stem Cells

Stem Cells Icon

Adds an extra Heart Container, heals a half heart, and increases Shot Speed.


Stigmata Icon

Boosts Isaac's damage by 0.3 and grants you one heart container.

Technology 2

Technology 2 Icon

Fires a continuous laser as you shoot tears. Decreases your damage by -35%.

Pierces enemies.


Toothpicks Icon

Increases shot speed.

Tough Love

Tough Love Icon

Isaac randomly shoots teeth instead of tears, dealing 3.2 times his normal damage.