The Binding of Isaac Wiki

Hives are enemies with a large rotting head inhabited by flies who can be found in The Caves and The Depths. They're fairly harmless but will spit out flies on occasion and release more on death. They might be considered an evolved form of Mulligans/Mulligoons, as they behave similarly to them and they sound the same when whimpering. Hives are considered to be a weaker version of The Duke of Flies as they both spit out flies and do not directly attack the player.


They act similar to Mulligans and Mulligoons, as they try to flee from the player. This frequently makes them run into dead ends or fireplaces. However, do not be fooled by their passive behavior; they will vomit flies if you are in their line of sight. On death, they will spawn up to five Attack Flies, Large Attack Flies, or Pooters. Unlike Mulligans and Mulligoons, Hives do not randomly explode.


The Hive's behavior gives the player the possibility to drive the Hives into edges or dead ends. If they are driven into corners or obstacles, it becomes much easier to kill them. They tend to vomit flies as you are shooting at them, though, so be careful about that.

It is not recommended to charge tears if the player has picked up Chocolate Milk. Charge shots will likely hit any flies a Hive has just vomited up as a last-ditch effort, thereby wasting the time it took to charge the shot.

Champion VariantsWrath of the Lamb DLC[]

Added in the Eternal Edition update, the Eternal Hive can be only fought at Hard Mode and, out of all enemies, comes with two unique types.

Eternal Normal Variant[]

Eternal Hive

This Eternal Hive variant vomits 2 flies at the player instead of 1, and bursts into flies, Fat Flies and Spiders on death.

Eternal Miniboss Variant[]

Eternal Boss Hive

A miniboss version of the Eternal Hive appears larger than weaker variants, has 2 Eternal Flies surrounding itself, and vomits Eternal Flies while running away from Isaac. It explodes into several Eternal Flies and Spiders on death, and will always drop an Eternal Heart.


  • The Gaper, Mulligan, Hive, and Swarmer are all the same monster in stages of decay and infestation. The Hive seems to be in the moderate stages of decay and infestation.
Fly variants FlyBlack FlyCUSTOMredflyAttack FlyMotersMoter • (Wrath of the Lamb DLC: White flyEternal Fly)
Gaper variants GaperGaperFrowninggaperFrowning GaperShape4336Mr. Maw • (Wrath of the Lamb DLC: Green gaperGurgle)
Mulligan variants MulliganMulliganMulligoonMulligoonHiveHive • (Wrath of the Lamb DLC: MulliboomMulliboom)
Horf variants HorfsHorfMawsMawRedmawRed Maw • (Wrath of the Lamb DLC: PsychicmawPsychic Maw)
Vis variants VisVis • (Wrath of the Lamb DLC: Vis FioDouble VisChubby VisChubber)
Maggot variants MaggotMaggotChargerChargerSpitySpitty
Hopper variants HopperHopperFHopperFlaming HopperLeaperLeaper
Boil variants BoilBoil • (Wrath of the Lamb DLC: Green boilGutWhite boilSack)
Clot variants ClottyClottyClot2ClotBlockadeI. Blob
Leech variants LeechLeechLeech2Kamikaze Leech • (Wrath of the Lamb DLC: Holy leechHoly Leech)
Spider variants Wrath of the Lamb DLC: Black spiderSpiderBig spiderBig SpiderSpider hopperTrite
Pooter variants PouterPooter • (Wrath of the Lamb DLC: SuperpooterFat Fly)
Boomfly variants BoomflyBoom FlySpitflyRed Boom Fly
Pacer variants PacerPacerGusherGusher
Sucker variants SuckerSucker • (Wrath of the Lamb DLC: PufferSpit)
Globin variants GlobinGlobinGlobin 2Gazing Globin
Knight variants KnightsKnightAlternative knightSelfless Knight
Eye variants EyeEyeEye2Bloodshot Eye
Host variants Host1HostHost2Red Host
Baby variants BobyBaby • (Wrath of the Lamb DLC: Angel babyAngelic Baby)
Eye variants EyeEyeEye2Bloodshot Eye
Poky variants PokiesPoky • (Wrath of the Lamb DLC: Spike trapSlide)
Brain variants BrainBrainMembrainMembrain
Gut variants GutsMonsterGuts • (Wrath of the Lamb DLC: Big gutsMama Guts)
Dople variants Dople1DopleDople 2Evil Twin
Grimace variants TurretStone Grimace • (Wrath of the Lamb DLC: VomitTurretVomit Grimace)
Keeper variants Wrath of the Lamb DLC: AvariceKeeperHang manHanger
Standalone variants ParabitePara-BiteFredFredLumpLumpEmbryoEmbryoPeep Eye • (Wrath of the Lamb DLC: SwarmheadSwarmerMask HeartMask + HeartCentipedeB. Licker)