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Not to be confused with the enemy Guts.

Guts are green-colored variants of regular Boils added in the Wrath of the Lamb expansion. They can replace regular Boils, and appear naturally in Necropolis.

Its bipedal variant, Walking Gut, appears in The Catacombs and Necropolis.

Behavior[]

Instead of firing multiple short-ranged blood shots, Guts fire explosive shots (similar to the IPECAC item) at Isaac that do not damage themselves.

They can easily be a nuisance if there are other enemies backing them. However, they are rather easy to manipulate into destroying rocks or finding Secret Rooms without using a bomb.

Champion Behavior[]

Eternal Guts fire three explosive shots instead of one. They are some of the easiest eternal enemies to defeat, as they still do not attack if they are not at full size.

It was added for the Eternal Edition update but can be exclusively encountered in Hard Mode.

Monsters
Fly variants FlyBlack FlyCUSTOMredflyAttack FlyMotersMoter • (Wrath of the Lamb DLC: White flyEternal Fly)
Gaper variants GaperGaperFrowninggaperFrowning GaperShape4336Mr. Maw • (Wrath of the Lamb DLC: Green gaperGurgle)
Mulligan variants MulliganMulliganMulligoonMulligoonHiveHive • (Wrath of the Lamb DLC: MulliboomMulliboom)
Horf variants HorfsHorfMawsMawRedmawRed Maw • (Wrath of the Lamb DLC: PsychicmawPsychic Maw)
Vis variants VisVis • (Wrath of the Lamb DLC: Vis FioDouble VisChubby VisChubber)
Maggot variants MaggotMaggotChargerChargerSpitySpitty
Hopper variants HopperHopperFHopperFlaming HopperLeaperLeaper
Boil variants BoilBoil • (Wrath of the Lamb DLC: Green boilGutWhite boilSack)
Clot variants ClottyClottyClot2ClotBlockadeI. Blob
Leech variants LeechLeechLeech2Kamikaze Leech • (Wrath of the Lamb DLC: Holy leechHoly Leech)
Spider variants Wrath of the Lamb DLC: Black spiderSpiderBig spiderBig SpiderSpider hopperTrite
Pooter variants PouterPooter • (Wrath of the Lamb DLC: SuperpooterFat Fly)
Boomfly variants BoomflyBoom FlySpitflyRed Boom Fly
Pacer variants PacerPacerGusherGusher
Sucker variants SuckerSucker • (Wrath of the Lamb DLC: PufferSpit)
Globin variants GlobinGlobinGlobin 2Gazing Globin
Knight variants KnightsKnightAlternative knightSelfless Knight
Eye variants EyeEyeEye2Bloodshot Eye
Host variants Host1HostHost2Red Host
Baby variants BobyBaby • (Wrath of the Lamb DLC: Angel babyAngelic Baby)
Eye variants EyeEyeEye2Bloodshot Eye
Poky variants PokiesPoky • (Wrath of the Lamb DLC: Spike trapSlide)
Brain variants BrainBrainMembrainMembrain
Gut variants GutsMonsterGuts • (Wrath of the Lamb DLC: Big gutsMama Guts)
Dople variants Dople1DopleDople 2Evil Twin
Grimace variants TurretStone Grimace • (Wrath of the Lamb DLC: VomitTurretVomit Grimace)
Keeper variants Wrath of the Lamb DLC: AvariceKeeperHang manHanger
Standalone variants ParabitePara-BiteFredFredLumpLumpEmbryoEmbryoPeep Eye • (Wrath of the Lamb DLC: SwarmheadSwarmerMask HeartMask + HeartCentipedeB. Licker)
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