The Binding of Isaac Wiki

Guppy's severed tail with bones showing at the end of one side.


Has a 1/3 chance to replace a pick up with a Chest or a Golden Chest when it drops, or a 1/3 chance to replace it with nothing at all.


  • If used in combination with the trinket The Left Hand every chest dropped will turn into a red one instead.
  • This item is especially useful in The Chest, where every dropped Chest will contain an item.


Can work well with the Skeleton Key, Flat Penny or a Golden Key, since the player will often have insufficient keys to open the increased amount of chests.

By using the The Left Hand a player can often quickly gather 2 of Guppy's other items, and transform into Guppy.


  • Can be found without unlocking it.
  • If the item is not in the Collection Page before the player initiates the 9 Deaths Challenge, it does not count as picking up the item, meaning it is not added to the Collection Page.

Related Achievements[]

Guppys Hairball

"Guppy's Hairball" - Collect three Guppy-related items in a single playthrough.