Guppy's Head is an activated item first added to the Wrath of the Lamb DLC for the original game, and also appear in the Rebirth remake. It is Guppy's decapitated head.
Effects[]
- Upon activation, 2-4 Blue Flies are spawned.
Synergies[]
- Chemical Peel - The attack flies spawned by this item will deal increased damage if the last shot fired was a Chemical Peel shot.
- When combined with two other Guppy items, (Dead Cat, Guppy's Tail or Guppy's Paw), Isaac will turn into Guppy. He will also gain The Mulligan effect and flight.
Trivia[]
- The item's icon from the original game is surrounded with flies.
Bugs[]
- From the original game, when entering a door while/right after using Guppy's Head, the flies will not spawn.