The Binding of Isaac Wiki

Globins (グロビン Gurobin) are child-like monsters appearing commonly in Chapter 2 and 3, and less commonly in The Womb, Utero, Cathedral, and Sheol.


They possess red, meat-like bodies, a few small teeth, and empty eye sockets.


Globins attempt to directly charge at the player, similar to Gapers; however, they are much faster. They'll deal full heart damage when contacted. Instead of dying, they will crumble into goo after taking a certain amount of damage and then regenerate anew unless destroyed in their puddle-of-goo form. If a Globin regenerates from their broken form, they will have decreased health, and will be easier to kill.

Because of their speed, Globins have the tendency to overshoot the player's position in rooms with a large number of obstacles, which can lead to Isaac being quickly surrounded on all sides if care is not taken. A tip on avoiding being surrounded is to remember that your tears do have moderate knockback that can open a window in a seemingly airtight formation.

Eternal Champion Behavior[]

Eternal Globin acts similarly to normal one, but moves slightly slower and releases 8-way bullets whenever it's reduced to its goo form.


  • They can be spawned by Mom.
  • Each time a Globin collapses, it counts as a kill. This can be exploited to either refill the recharge bar for items, or with the Charm Of The Vampire, to (slowly) refill health and increase damage with Bloody Lust, although patience is required for these.
  • Standing over an unreachable spot (via The Ladder or Flight) will cause Globins to stop moving towards Isaac, and stand completely still, increasing Isaac's chance to defeat them real easily without decreasing his health. They will not move again until Isaac becomes reachable again.
  • When Globins and Gazing Globins are spawning into a room, they can be killed without collapsing.
  • In Rebirth, a single Globin can be spawned if Isaac kills the Swinger by the head.


  • Globins are a reference to Red/Blood Skeletons from Castlevania.[1]
  • The name most likely stems from Hemoglobin, a biomolecule responsible for giving blood its red color.[2]
  • Sloth and Super Sloth are reskinned versions of Globins.
  • Globins use to make a squishing sound while regenerating anew in the original game. The sound from Rebirth, however, is missing. That also goes to the Gazing Globin.


Fly variants FlyBlack FlyCUSTOMredflyAttack FlyMotersMoter • (Wrath of the Lamb DLC: White flyEternal Fly)
Gaper variants GaperGaperFrowninggaperFrowning GaperShape4336Mr. Maw • (Wrath of the Lamb DLC: Green gaperGurgle)
Mulligan variants MulliganMulliganMulligoonMulligoonHiveHive • (Wrath of the Lamb DLC: MulliboomMulliboom)
Horf variants HorfsHorfMawsMawRedmawRed Maw • (Wrath of the Lamb DLC: PsychicmawPsychic Maw)
Vis variants VisVis • (Wrath of the Lamb DLC: Vis FioDouble VisChubby VisChubber)
Maggot variants MaggotMaggotChargerChargerSpitySpitty
Hopper variants HopperHopperFHopperFlaming HopperLeaperLeaper
Boil variants BoilBoil • (Wrath of the Lamb DLC: Green boilGutWhite boilSack)
Clot variants ClottyClottyClot2ClotBlockadeI. Blob
Leech variants LeechLeechLeech2Kamikaze Leech • (Wrath of the Lamb DLC: Holy leechHoly Leech)
Spider variants Wrath of the Lamb DLC: Black spiderSpiderBig spiderBig SpiderSpider hopperTrite
Pooter variants PouterPooter • (Wrath of the Lamb DLC: SuperpooterFat Fly)
Boomfly variants BoomflyBoom FlySpitflyRed Boom Fly
Pacer variants PacerPacerGusherGusher
Sucker variants SuckerSucker • (Wrath of the Lamb DLC: PufferSpit)
Globin variants GlobinGlobinGlobin 2Gazing Globin
Knight variants KnightsKnightAlternative knightSelfless Knight
Eye variants EyeEyeEye2Bloodshot Eye
Host variants Host1HostHost2Red Host
Baby variants BobyBaby • (Wrath of the Lamb DLC: Angel babyAngelic Baby)
Eye variants EyeEyeEye2Bloodshot Eye
Poky variants PokiesPoky • (Wrath of the Lamb DLC: Spike trapSlide)
Brain variants BrainBrainMembrainMembrain
Gut variants GutsMonsterGuts • (Wrath of the Lamb DLC: Big gutsMama Guts)
Dople variants Dople1DopleDople 2Evil Twin
Grimace variants TurretStone Grimace • (Wrath of the Lamb DLC: VomitTurretVomit Grimace)
Keeper variants Wrath of the Lamb DLC: AvariceKeeperHang manHanger
Standalone variants ParabitePara-BiteFredFredLumpLumpEmbryoEmbryoPeep Eye • (Wrath of the Lamb DLC: SwarmheadSwarmerMask HeartMask + HeartCentipedeB. Licker)