IsaacHDIsaac Rebirth

And when He had opened the third seal, I heard the third beast say, Come and see. And I beheld, and lo a black horse, and he that sat on him had a pair of balances in hand.

–Revelations 6:5

Famine is one of the four Horsemen of the Apocalypse, a boss encountered in the Basement or Cellar after you beat the game for the first time.

He appears as an eyeless, grinning humanoid with cracked lips riding upon a hobby horse, both of which are severely emaciated.

Just like the other three harbingers, Pestilence, War and Death, he will drop a Cube Of Meat or Ball of Bandages when defeated, which cannot be re-rolled with the Dice. Some also refer to him as "Faminic," as this was his name in scripture.


Phase 1 Famine

Famine will begin his fight with a very fast charge to the left or right that will make him go through the walls and come back from the other side, stopping at his original location. After that, he will stay in practically the same spot and spawn a Pooter or a Fat Fly, capable of having a maximum of two at any given time.

For as long as these flies are on-screen, he will not move around much and will not charge until Isaac gets in his line of sight. These charges will destroy any flies in the way, so it can be an effective strategy to force him to charge as much as possible.

Phase 2

Famine head When he only has a third of his health left, his body and horse will be destroyed leaving only the head, and he will start saying "hey" as pestilence does in his first phase. He won't be able to move around much or spawn any more flies, but it will fire fast-moving triple shots (one in the center and two in a split pattern to the sides) directly at Isaac's location.


  • The charge deals a full heart of damage, instead of the usual half-heart damage found in the Basement/Cellar.

Champion Variants


Famine blue

Phase one attacks in a six-way pattern (no bullets in vertical directions). He also charges faster, at a much higher rate than normal. While charging, he moves slightly (diagonally if needed) towards Isaac, and makes a complete charge around the room rather than just stopping short as per his non-champion form. When he loses his body and horse, he'll attack by vomiting bullets similar to Scolex or Monstro.


Eternal Famine

Phase one's charge attack does not go through the walls, instead stopping at the end of the room. During its charge it shoots a ring of projectiles. His attack shoots a volley of projectiles in random directions, and spawns four Pooters and/or Fat Flys around him. Phase two's attack shoots an additional 2 projectiles in a split pattern after the initial 3 projectiles.



  • On rare occasions, Famine may use his charge attack and push Isaac into the wall behind the rocks. If the player has no bombs, they may be permanently trapped and the playthrough will need to be restarted.
  • On later floors, Famine's health is not sufficient to qualify as a boss. Therefore, if encountered with another boss, hurting him will not change the displayed health meter. If encountered alone (like in the Cathedral), there will be no health bar.
  • When battling Famine (In Phase 2) with the item Mom's Contacts, there's a chance for him to vanish, trapping the player, unless they have Teleport!, a Tarot Card that teleports you, or a Telepill.
  • On rare occasions, Famine may use his charge attack and push Isaac in the Devil Room (even in the Basement/Cellar 1). If Isaac walks out the room, Famine will have to be fought again, with restored health.


  • Famine is pale brown, but he is described as black in the Bible.
  • Famine has orange glowing eyes in his Rebirth intro screen.


The Harbingers Related
Famine Pestilence War Death Conquest Headless ingame
Famine Pestilence War Death Conquest Headless Horseman

Regular Bosses
BlastocystChubDaddy Long LegsDark OneDingleDuke of FliesThe FallenFistulaGeminiGurdyGurdy Jr.GurglingsThe HauntLarry Jr.LokiMama GurdyMask of InfamyMega FattyMega MawMonstroMr. FredPeepPinPolycephalusScolexTurdlingsWidow

Afterbirth: BrownieDangleLittle HornRag ManTurdlings
Afterbirth †: Big HornRag Mega
Antibirth-only: Baby PlumBeelzeblubChimeraGreat GideonHornfelThe RainmakerReap CreepRotgutThe ScourgeThe SirenTuff TwinsWormwood

Posthumous Bosses
The AdversaryThe Blighted OvumThe BloatThe CageCarrion QueenThe GateThe HollowThe HuskLokiiMonstro IITeratomaThe Wretched

Afterbirth: The ForsakenThe FrailThe Stain
Antibirth-only: The HereticThe PileThe Visage

Alternative Bosses

Afterbirth †: Sisters Vis

ConquestWarFamineDeathPestilenceHeadless Horseman
Final Bosses
???IsaacIt LivesThe LambMega SatanMomMom's HeartSatan

Afterbirth: HushUltra Greed
Afterbirth †: Delirium
Antibirth-only: The Witness

Seven Deadly Sins
Seven Super Deadly Sins
Super EnvySuper GluttonySuper GreedSuper LustSuper PrideSuper SlothSuper WrathUltra Pride
Angels / Demons
KrampusGabrielUrielFallen Angels
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