- Not to be confused with the soundtrack Empty Vessels.
Isaac wears the Empty Vessel as a necklace.
- Grants 2 black hearts.
- If Isaac has soul/black hearts but with no red hearts at all:
- Grants flight.
- Every 40 seconds, when in a room with monsters, the Book Of Shadows triggered, creating a shield that nullifies all types of damage for 10 seconds.
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