Appears as a brown bottle with a green label. The label has a skull-and-crossbones on it.
- Removes the skin from the left side of Isaac's head.
- Tears fired from left eye have increased damage.
- When used with Cain, tears will have a 50% chance to do increased damage.
- The Mulligan, Infestation, Guppy's Head, Guppy - The attack flies spawned by these items will deal increased damage if the last shot fired was a Chemical Peel shot.
- Brimstone, Technology - Every second laser fired will deal increased damage.
- Loki's Horns - Cross pattern will increase in damage if fired from left eye