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Brimstone is a passive item.

It appears as an alchemical symbol for sulfur.

Effects

Isaac appears demonic with large curved horns and an angry expression.

Picking up Brimstone will multiply Isaac's current damage by 3. It also changes tears to a chargeable laser that pierces all objects in its path (including enemies, environmental hazards and walls). It can only be fired after a short charge-up period (approximately 1-2 seconds until Isaac's head begins flashing red). Each laser is emitted for about one second and hits twice, so it is possible to destroy some two-stage enemies in one shot (Globins and Hives along with the flies they spawn on death), or to strafe the shot over multiple enemies.

It is possible to charge before entering a room so that the first shot can be fired immediately. Even if Isaac have not finished charging Brimstone when he'll pass through a door, it is always fully charged once a new room is entered if the fire button is still being held.

Notes

  • Attempting to fire the beam before it is fully charged will cancel the charge.
  • Getting hit while charging will reset the charge.
  • An increased damage stat does increase Brimstone's damage.
  • If the player has an item like Transcendence, Isaac will get wings instead of losing his body.
  • Despite common belief, an increased tears stat does not reduce the charge up time of Brimstone. But a decreased one does make it longer.
  • This item has 75% lower chance to appear in Hard Mode.

Interactions

Synergies

  • Chocolate Milk - Allows partial charge doing damage in relation to charging time, but Brimstone will charge slower than it shows (e.g. head flashes before fully charged). Charging before entering a room will result in the appearance of a full charge, but the fired shot will not damage enemies.
  • The Inner Eye, Mutant Spider, IPECAC - Brimstone charges slower (3-4 sec) but has tripled damage.
    • These damage increases do not stack with each other.
  • Sacred Heart - Damage of the laser is greatly increased, with a slightly longer charge time.
  • Polyphemus - Brimstone charges more slowly, but damage is increased exponentially (enough to one or two-shot most bosses.)
    • Actual damage bonus is (bonus from Polyphemus) * 3, so overall bonus decreases if stacked with The Inner Eye/Mutant Spider.
  • The Common Cold - Laser has chance for poisoning enemies for 2.5 seconds.
  • Spider's Bite - Laser has a chance to slow enemies down for 2.5 seconds.
  • Mom's Contacts - Laser has chance to freeze enemies as a normal tear would.
  • A Lump of Coal - Increased Damage (+2). This is inside of the 3x multiplier that brimstone gives, and the 2x multiplier from Polyphemus.
  • Curved Horn- Similar to A Lump Of Coal, increases damage by +2 inside the 3x multiplier. Is affected by the 3x multiplier from the synergy between Brimstone and Polyphemus, but not the 2x multiplier from Polyphemus.
  • Number One - Decreases charge time with no side effects.
  • Technology 2 - Can shoot the Technology 2 laser while charging, but damage decreases. If playing as Cain, he will never be able to shoot the blood laser.

Trivia

  • According to the Bible, "Brimstone", which is possibly the ancient name for sulfur, evokes the acrid odor of volcanic activity. It is used in conjunction with Fire in the phrase Fire and brimstone, an idiomatic expression of signs of God's wrath, often appearing in reference to the fate of the unfaithful. The term is also used, sometimes pejoratively, to describe a style of Christian preaching that uses vivid descriptions of judgment and eternal damnation in Hell to encourage repentance.
  • The symbol that represents Brimstone is known as the Leviathan Cross, the alchemical symbol for Sulfur. Due to Sulfur's association with Hell, it is also used as a Satanic symbol.
  • Horns resembling Brimstone's own were added to Team Fortress 2 on the December 3rd, 2014 patch.

Bugs

  • Release Brimstone and tap multiple times in the direction Isaac fired. This will increase Brimstone's hit times from 2 to a maximum of 4 times, effectively doubling the damage. The beam will visually go downwards despite actually fired in the direction Isaac originally did. Doesn't work with Chocolate Milk.
    • This bug was popularized by a YouTuber called Bisnap and named Brimsnap by a streamer called "CobaltStreak".
    • If Brimsnap is used and it coincides with Robo-Baby's laser, it will glitch out and be deformed.
  • Brimstone's charge (open mouthed laser) will overlap any item that is on the player's face; this is obviously a graphical bug.
  • If collected with Mini Mushroom and/or Odd Mushroom (Thin), the Brimstone shot will stop short of the room (horizontally). This is purely aesthetic, and enemies can still be hit, even if the shot does not reach them.
Items
Passive Items Tear Modifiers: The Inner EyeSpoon BenderMy ReflectionSkatoleCube of MeatCupid's ArrowDr. FetusMom's EyeWiggle WormTechnologyChocolate MilkLoki's HornsLittle ChubbySpider's BiteThe Common ColdThe ParasiteMom's ContactsMom's KnifeOuija BoardBrimstoneA Lump of Coal

(Wrath of the Lamb DLC: IPECACTough LoveTechnology 2Mutant SpiderEpic FetusPolyphemusSacred Heart)

Stat Ups: The Sad OnionMax's HeadNumber OneBlood of the MartyrMagic MushroomRoid RageRaw LiverLunchDinnerDessertBreakfastRotten MeatWooden SpoonThe BeltMom's UnderwearMom's HeelsMom's LipstickWire Coat HangerStevenPentagramThe MarkGrowth HormonesMini MushroomThe PactSmall RockSuper BandageRobo-BabyLittle C.H.A.D.Little GishLittle SteveThe RelicThe HaloMoney Equals PowerBlood BagOdd Mushroom (Thin)Odd Mushroom (Large)Whore Of BabylonBucket Of Lard
(Wrath of the Lamb DLC: StigmataSpeed BallChemical PeelBloody LustCat-O-Nine-TailsStem CellsTooth PicksSMB Super Fan!MEAT!Magic 8 BallSqueezyJesus Juice)

Familiars and Orbitals: Brother BobbyHalo Of FliesDistant AdmirationSister MaggyGuardian AngelDemon BabyDead BirdForever AloneSack Of PenniesBomb Bag
(Wrath of the Lamb DLC: Bum FriendThe PeeperGhost BabyHarlequin BabyDaddy LonglegsSacrificial DaggerRainbow BabyHoly WaterGuppy's Hair BallAbel)

Others: 1UPThe VirusLess Than ThreeSkeleton KeyA DollarA QuarterBoom!TranscendenceThe CompassPHDRosaryXRay VisionLucky FootMagnetoTreasure MapThe LadderCharm Of The VampireThe BatterySteam SaleDead CatLord Of The PitSpelunker HatMr. MegaThe Wafer9 VoltBobby-Bomb
(Wrath of the Lamb DLC: Guppy's TailMom's PurseBob's CursePageant BoyScapularInfestationThe MulliganHabitSpirit Of The NightAnkhCeltic CrossMitreFateThe Black BeanHoly GrailDead DovePyro3 Dollar BillMom's Coin PurseBox)

Activated Items Base Items: The PoopMr. BoomTammy's HeadMom's BraKamikazeMom's PadBob's Rotten HeadTeleport!My Little UnicornYum HeartDoctor's RemoteShoop Da Whoop!Lemon MishapThe HourglassThe NailWe Need To Go Deeper!Deck of CardsMonstro's ToothThe GamekidMom's Bottle of PillsThe DiceThe Pinking ShearsThe BeanDead Sea ScrollsRazor BladeForget Me NowA Pony

(Wrath of the Lamb DLC: Guppy's PawIV BagBest FriendRemote DetonatorGuppy's HeadPrayer CardNotched AxeCrystal BallCrack The SkyThe CandleD20Spider ButtDad's KeyPortable SlotWhite PonyBlood Rights)

Books: The BibleThe Book of BelialThe NecronomiconBook Of RevelationsBook of ShadowsAnarchist CookbookThe Book Of SinMonster Manuel
(Wrath of the Lamb DLC: Telepathy for Dummies)

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