Angel Room

Angel Room is a special room that was added in the Wrath of the Lamb DLC. The Angel Room can replace the Devil Room on any floor. Like the Devil Room, it presents a simple offering. However, instead of Satan sitting there, an angel has taken his place.

These items require no hearts to pick up, and draw from a different Item Pool than the Devil Room. While Devil Room items are centered around offense, most Angel Room items are centered around defense, with effects that typically involve soul hearts or flight.

The room takes on the appearance of a Cathedral room, with stained-glass windows covering the walls. There seems to be a crying Isaac design on some of the windows.

Chances of appearing

Angel Rooms can replace Devil Rooms and share the same spawn as Devil Rooms with the following added conditions:

• A Devil Room has spawned at some point since launching the game
• No deals with the devil have been taken in the run

If these two conditions are met, the next Devil Room has a 50% chance of being replaced by an Angel Room.

The chance to see Angel Rooms will carry over between runs in a play session. This means that if you trigger Angel Rooms and take the item they hold, they will have the same chance to appear in the next run unless you close the game and reopen it between runs. Note that taking an item from the Angel Room will cause the next two floors to have a reduced chance of having an Angel Room spawn, following the rules of the Devil Room.

Items Offered

These are items found inside of the Angel Room.

Item	Icon	Effect
The Bible		Upon activation, Isaac gains Flight, allowing him to pass over all obstacles in the current room. Instantly kills Mom, Mom's Heart and It Lives when activated, will kill Isaac when activated while fighting Satan, Isaac or ??? unless he has The Wafer.
Blood Of The Martyr		Increases Damage by 1, and turns Isaac's tears into blood tears. If collected with the The Book of Belial, damage will also be multiplied by 1.5x upon activation.
Dead Dove		Gives Isaac spectral tears and flight.
Guardian Angel		Spawns a Guardian Angel that orbits Isaac. Does damage on touch, blocks shots and doubles the speed of other orbitals.
The Halo		Increases all stats (Including Heart Containers) by one.
Holy Grail		Adds 1 empty heart container and gives flying ability.
Mitre		Greatly increases the chance of replacing spawned hearts with soul hearts.
Prayer Card		Grants half an Eternal Heart per use.
The Relic		Isaac is followed by a small blue cross that will drop a Soul Heart every 5 rooms.
Sacred Heart		Shots are larger, travel slower and home in on enemies. Damage is multiplied. (Multiplies damage by X2.3+1, -0.4 tears, -0.25 shot speed.) Gives 1 Soul Heart and restores full Health on Pick up.
Scapular		Once per room, when Isaac is reduced to his last half red Heart, the aura around his head temporarily vanishes and he is granted one Soul Heart.

Notes

• The Angel Room may appear instead of the Devil Room after defeating Mom's Heart. However, it offers a trapdoor that sends you to Sheol rather than a beam of light that brings you to the Cathedral. This is because the Angel Room is treated as the Devil Room coding-wise. (In Rebirth, there will be a beam of light, and it will take you to the Cathedral.)
• Leaving the Boss room prior to entering the Angel Room may cause it to disappear; losing the opportunity to receive an item.
• If the Joker card is used on a floor which has an Angel Room, it will send you to that Angel Room instead of a Devil Room.
• Items in the Angel Room do not cost hearts as opposed to the Devil Room.

Bugs

• It is possible for the Angel Room to spawn but offer no item. Possibly due to Krampus spawning code.

Gallery

The Angel Room while an Angel offers the Sacred Heart item prior to 1.3. Note the devil room door.

Angel room after the defeat of Mom's Heart

Trapdoor to Sheol in the Angel Room. Note the fireplaces.

Angel room offering The Relic

Angel room offering the Dead Dove

Trivia

• The reason the angel is missing a face is likely a reference to the Bible passage Exodus 33:20: "But," he said, "you cannot see my face, for man shall not see me and live."
• On his Tumblr, Edmund McMillen stated the angel's lack of a face is due to the way God is portrayed in Chick tracts by Jack T. Chick, from whom McMillen takes inspiration.